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MARBURG VIRUS VACCINE
The invention here relates to recombinant DNA constructs which comprise a Venezuelan equine encephalitis replicon vector and at least one DNA fragment encoding a protective antigen from the Marburg virus. The DNA constructs are useful for inducing an immune response which is protective against infection with Marburg virus in nonhuman primates.
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Inventor(s):HEVEY, M.; NEGLEY, D.; PUSHKO, P.; SMITH, J.; SCHMALJOHN; A.