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PRACTICAL SEROLOGICAL ASSAY FOR THE CLINICAL DIAGNOSES OF LEISHMANIASIS

Methods for the diagnosis of visceral, cutaneous and canine leishmaniasis in a subject suspected of being infected with the parasitic protozoa Leishmania is disclosed. Disclosed are antibody-capture enzyme-linked immunosorbent assays (ELISAs) for the detection of antibodies to Leishmania parasite soluble antigens and antigen-capture ELISAs for the detection of Leishmania parasite soluble antigens in host samples. Also disclosed are immunodiagnostic kits for the detection of Leishmania parasite circulating antigens or IgM and IgG antibodies in a sample from subject having visceral, cutaneous or canine leishmaniasis. In these methods and kits, detection may be done photometrically or visually. The methods and kits also allow the visualization of Leishmania amastigotes or promastigotes in a sample.


Docket:WRAIR 98-41

Publication/Issued No.:7,008,774

Publication/Issue Date:2006-03-07

Categories: Assay

More Detail:Visit USPTO.GOVExternal link

Lab:WRAIR

Inventor(s):RYAN, J.; MARTIN, S.; SMITHYMAN, A.


For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@mail.mil
 

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