Technologies Available for Licensing
BURST –FREE SUSTAINED RELEASE POLY-(LACTIDE/GLYCOLIDE) MICROSPHERES
Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1 100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer as a blend of uncapped (free carboxyl end group) and end-capped forms ranging in ratios from 100/0 to 1/99.
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Inventor(s):JEVANTHI, R.; VAN HAMMONT, J.; FRIDEN, P.; REID, R.; ROBERTS, D.; MCQUEEN, C.; SETTERSTROM, J.