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For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@mail.mil



2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF

Disclosed herein are 2-guanidinylimidazolidinedione compounds having the structural formula A or B ##STR00001## wherein R.sup.1 and R.sup.2 are each independently a hydrogen, halogen, alkyl, alkoxyl, amino, alkylamino or aralkyl, and wherein R.sup.3 is an alkyl, cycloalkyl, heterocycloalkyl, acyl, aryl, heteroaryl, alkylaryl, sulfonyl, alkylsulfonyl, and pharmaceutically acceptable salts thereof, and methods of making thereof. Also disclosed are methods of treating, preventing, or inhibiting malaria with the 2-guanidinylimidazolidinedione compounds, and pharmaceutical compositions comprising the 2-guanidinylimidazolidinedione compounds, and kits.


Docket:WRAIR 2003-10

Publication/Issued No.:7,101,902

Publication/Issue Date:2006-09-05

Categories: Vaccine

More Detail:Visit USPTO.GOVExternal link

Lab:WRAIR

Inventor(s):LIN, A.; ZHANG, Q.; GUAN, J.; MILHOUS, W.


For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@mail.mil
 

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