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INDUCTION OF HUMOR IMMUNITY BY VARIANTS OF FOLATE BINDING PROTEIN
The present invention is directed to variants of antigens comprising folate binding protein epitopes as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by energy, as in unresponsiveness.
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Inventor(s):IOANNIDES, C.; PEOPLES, G.