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RECOMBINANT CHIMERIC HUMAN ANTI-BOTULINUM ANTIBODIES
In this application is described the production of recombinant, chimeric, humanized antibodies specific for both BoNt/A and BoNT/B. The humanized antibodies were converted from a mouse anti-BoNT/A/B Fab fragment into a whole human IgG1 antibody. The antibodies are useful in assays for detecting human exposure to BoNT/A and BoNT/B.
Categories: Antibody Technologies
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Inventor(s):PALYS, T.; SCHOEPP, R.; SCHMID K.