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In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-1.sub.42. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1.sub.42 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.

Docket:WRAIR 2002-32

Publication/Issued No.:8,211,447

Publication/Issue Date:2012-07-03

Categories: Method

More Detail:Visit USPTO.GOVExternal link


Inventor(s):ANGOV, E.; DARKO, C.; LYON, J.

For Licensing Opportunities, please contact the ORTA at


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