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DERIVATIVES OF MEFLOQUINE AND ASSOCIATED METHODS FOR MAKING AND USING

The present invention relates to new mefloquine derivatives and therapeutic compositions comprising one or more mefloquine derivatives. Mefloquine derivatives of the invention have a pentafluorosulfanyl moiety substitution at the 8-position. Certain mefloquine derivatives further include a quinoline methanol moiety substitution at the 4-position. The present invention also relates to new intermediate compounds useful in the synthesis of the mefloquine derivatives, which intermediates also have a pentafluorosulfanyl moiety substitution at the 8-position.


Docket:WRAIR 2010-11

Publication/Issued No.:WO 2010/144434

Publication/Issue Date:2010-12-16

Categories: Treatment

More Detail:Visit WIPO.INTExternal link

Lab:WRAIR

Inventor(s):DOW, G.


For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@mail.mil
 

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