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In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) AMA-1 ectodomain. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant AMA-1 is useful as a diagnostic reagent, for use in antibody production, and as a protein for use alone, or as part of, a vaccine to prevent malaria.

Docket:WRAIR 01-33

Publication/Issued No.:7,029,685

Publication/Issue Date:2006-04-18

Categories: Method

More Detail:Visit USPTO.GOVExternal link


Inventor(s):LANAR, D.; DUTTA, S.; WARE, L.; NAIR, L.

For Licensing Opportunities, please contact the ORTA at

Last Modified Date: 28 Aug 2019

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