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COMPOSITIONS OF AND METHODS OF USING LIGAND DIMERS

Provided herein are ligand dimers, compositions thereof, as well as methods of their use. The ligand dimers provided can comprise at least one ligand to a Her receptor and can be used to force dimerization of specific receptor pairs. The forced dimerization of specific receptor pairs can be used to control (e.g., promote or inhibit) signaling, and, therefore, the ligand dimers provided can also be used in various forms of treatment in which such signaling control is beneficial to a subject. It follows that methods for controlling signaling are provided as are various methods of treatment.


Docket:MEDCOM 15-14

Publication/Issued No.:9,198,952

Publication/Issue Date:2015-12-01

Categories: Method,Treatment

More Detail:Visit USPTO.GOVExternal link

Lab:MEDCOM

Inventor(s):ALVAREZ, LUIS


For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@mail.mil
 

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